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mnaA [2019-07-12 10:10:50]
UDP-N-acetylglucosamine 2-epimerase
function
biosynthesis of teichoic acid
product
UDP-N-acetylglucosamine 2-epimerase
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.4|Biosynthesis of teichoic acid][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.3|Biosynthesis of teichoic acid][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]Gene
Coordinates
3,664,241 3,665,383
Phenotypes of a mutant
essential [Pubmed|12682299]The protein
Catalyzed reaction/ biological activity
UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine (according to Swiss-Prot)Protein family
UDP-N-acetylglucosamine 2-epimerase family (according to Swiss-Prot)Structure
[PDB|1O6C] [Pubmed|16021622][SW|Localization]
cytoplasm (according to Swiss-Prot)Expression and Regulation
Operons
genes
[gene|7BEAEDC0BE19F490B597BB0A6AEAE006FFBDC1D1|mnaA]
description
[Pubmed|22383849]
view in new tabBiological materials
Mutant
MGNA-B651 (yvyH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1650 NBRP B. subtilis, Japan]References
Reviews
Original publications
12107153,16021622,24470206